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We suggest the following publications (selection).

General References:

Hanahan D, Weinberg RA (2000):
The Hallmarks of Cancer
Cell 100: 57-70

Zur Hausen H (2006):
Infections causing human cancer
Weinheim 2006

Kamb A (2005):
What's wrong with our cancer models?
Nat. Rev. Drug. Discv. 4:161-165

Trosko JE, Chang CC, Madhukar BV, Dupunt E (1995):
Intercellular communication: a paradigm for the
interpretation of the initiation/promotion/progress
model of carcinogenesis

In: Arcos JC (Ed.): Chemical induction of cancer:
modulation and combination effects.
Boston, MA: 205-222

Vester F, Henschel G (1990):
Krebs. Fehlgesteuertes Leben
München 1990

Weinberg RA (2007):
The biology of Cancer
New York

References to special aspects of cancer research:

From Intra cellular Communication to Tumors as
autonomous Organs

Intra cellular Communication

Alirol E, Martinou JC (2006):
Mitochondria and cancer: is there a morphological connection?

Calin GA, Croce CM (2006):
MicroRNA signatures in human cancers
Nat Rev Cancer 6: 857-866

Dalmay T, Edwards DR (2006):
MicroRNAs and the hallmarks of cancer
Oncogene 25:6170-6175

Li L, Zou L (2005):
Sensing, signaling, and responding to DNA damage:
organization of the checkpoint pathways in mammalian cells

J Cell Biochem 94:298-306

Inter cellular Communication

Massagué J (2000):
How cells read TGF-ß signals?
Nat. Rev. Mol. Cell. Biol. 1:169-178

Perbal, B (2003):
Communication is the key
Cell Signaling and Communication. 1:3.

Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH (2004):
Nanotubular highways for intercellular organelle transport

de la Taille A, Chen MW, Burchardt M, Chopin DK, Buttyan R (1999):
Apoptotic conversion: evidence for exchange of genetic
information between prostate cancer cells mediated by apoptosis

Cancer Res 59:5461-5463

Trosko JE (2007):
Gap junctional intercellular communication as a
biological "Rosetta stone" in understanding,
in a systems biological manner, stem cell behavior,
mechanisms of epigenetic toxicology, chemoprevention
and chemotherapy

J Membr Biol 218:93-100

Cancer Stem Cells

Dalerba P, Cho RW, Clarke MF (2007):
Cancer stem cells: models and concepts
Annu Rev Med 58:267-284

Reya, T, Morrison SJ, Clake MF, Weissmann JL (2001):
Stem cells, cancer and cancer stem cells.
Nature 414:105-111

Trosko, JE (2004):
Ignored Hallmarks of Carcinogenesis: Stem Cells
and Cell-Cell-Communication.

In: Bradlow LH, Castagnetta L, Massimo L, Zaenker K (Eds.):
Signal Transduction and Communication in Cancer Cells.
New York, 192-201

Vermeulen L, Sprick MR, Kemper K, Stassi G, Medema JP (2008):
Cancer stem cells - old concepts, new insights
Cell Death Differ 15:947-958

Cancer: A Complex Tissue Disease

Barcellos-Hoff MH (2001)
It takes a tissue to make a tumor:
epigenetics, cancer and the microenvironment. J Mammary

Gland Biol Neoplasia 6:213 221

Weinstein IB, Gattoni CS, Kirschmeyer P et al. (1984):
Multistage carcinogenesis involves multiple genes
and multiple mechanisms

J. Cell Physiol. Suppl. 3: 127-137

Wilson S, Jones L, Coussens C, Hanna K (eds.) (2002):
Cancer and the Environment: Gene-Environment Interaction.
Washington D.C.

Cancer and Epigenetics

Esteller M (2008):
Epigenetics in cancer
N Engl J Med. 358:1148-1159

Esteller M, Herman JG (2002):
Cancer as an epigenetic disease: DNA methylation
and chromatin alterations in human tumours

J Pathol.196:1-7

Feinberg AP, Tycko B (2004):
The history of cancer epigenetics
Nat Rev. Cancer. 4:143-153

Cancer and Inflammation

Clevers H (2004):
At the crossroads of inflammation and cancer.
Cell 118:671-674

Coussens LM, Werb Z. (2002):
Inflammation and cancer
Nature 420:860-867

Cancer as a "self-governed" Organ

Bisell MJ, Radisky D (2001):
Putting tumors in context
Nat. Ref. Cancer 1: 46-54

Radisky DM, Hagios C., Bisell MC (2001):
Tumors are unique organs defined by abnormal signaling and context
Semin. Cancer Biol. at Rev Mol Cell Biol, 11: 87-95

Intervention Concepts with use of Viruses and Bacteria

Anderson JC, Clarke EJ, Arkin AP, Voigt CA (2006):
Environmentally controlled invasion of cancer cells
by engineered bacteria

J Mol Biol 355: 619-627

Benencia F, Coukos G (2008):
Biological therapy with oncolytic herpesvirus
Adv Exp Med Biol 622:221-233

Ryan RM, Green J, Lewis CE (2006):
Use of bacteria in anti-cancer therapies
Bioessays.28 :84-94


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